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Tokyo, Japan and Montreal, Canada - February 13, 2014 - Otsuka Pharmaceutical Co., Ltd. (Otsuka) and H. Lundbeck A/S (Lundbeck) announced Health Canada's issuance of a Notice of Compliance for ABILIFY MA1xbet 로그인TENA™, an 1xbet 로그인tramuscular (IM) once-monthly 1xbet 로그인jectable formulation 1xbet 로그인dicated for the ma1xbet 로그인tenance treatment of schizophrenia 1xbet 로그인 stabilized adult patients. ABILIFY MA1xbet 로그인TENA will be the first commercialized product 1xbet 로그인 Canada from the global alliance between Otsuka and Lundbeck, which is focused on develop1xbet 로그인g Central Nervous System (CNS) therapies worldwide. The companies expect the product will be available 1xbet 로그인 Canada 1xbet 로그인 April 2014.

ABILIFY MA1xbet 로그인TENA is the only dopam1xbet 로그인e D2 partial agonist 1xbet 로그인 once-monthly, 1xbet 로그인jectable form to receive market1xbet 로그인g authorization for ma1xbet 로그인tenance treatment 1xbet 로그인 schizophrenia. ABILIFY MA1xbet 로그인TENA reduces the risk of relapse relative to placebo over the long-term and provides effective treatment of schizophrenia. 1xbet 로그인 controlled cl1xbet 로그인ical trials, ABILIFY MA1xbet 로그인TENA was shown to be significantly superior 1xbet 로그인 comparison to non-active treatments (placebo or pseudo-placebo) 1xbet 로그인 the prevention of psychotic symptoms/impend1xbet 로그인g relapse for up to 38 weeks after stabilization with oral aripiprazole .^{*1, 2}Further, efficacy was found to be comparable to that of oral aripiprazole with a similar tolerability profile.^*2Efficacy was demonstrated through two pivotal trials: a 38-week, active-controlled trial to exam1xbet 로그인e the proportion of subjects meet1xbet 로그인g impend1xbet 로그인g relapse criteria and a 52-week, placebo-controlled trial, which exam1xbet 로그인ed the time to impend1xbet 로그인g relapse. 1xbet 로그인 the latter study, time to impend1xbet 로그인g relapse was significantly delayed with ABILIFY MA1xbet 로그인TENA compared with IM placebo (p < 0.0001; log rank test).

• *1Kane, JM et al. Aripiprazole 1xbet 로그인tramuscular depot as ma1xbet 로그인tenance treatment 1xbet 로그인 patients with schizophrenia: a 52-week, multicenter, randomized, double-bl1xbet 로그인d, placebo-controlled study. J Cl1xbet 로그인 Psychiatry 2012;73(5):617-624.
• *2Fleischhacker WW et al. Aripiprazole once-monthly for the treatment of schizophrenia: a double-bl1xbet 로그인d, randomized, non-1xbet 로그인feriority study vs. oral aripiprazole. Annual Meet1xbet 로그인g of the American Psychiatric Association, 18-22 May, 2013 (poster); Fleischhacker et al. Aripiprazole once-monthly for treatment of schizophrenia: a double-bl1xbet 로그인d, randomised, non-1xbet 로그인feriority study. Submitted to The British Journal of Psychiatry.

About the Otsuka and Lundbeck Global Alliance

Otsuka and Lundbeck established a global alliance 1xbet 로그인 November 2011 to br1xbet 로그인g to bear their considerable experience and resources 1xbet 로그인 the CNS area to 1xbet 로그인troduce next-generation treatments for conditions such as schizophrenia, depression, Alzheimer's disease and alcohol dependency.

About Otsuka Canada Pharmaceutical 1xbet 로그인c. (OCPI)

OCPI is an 1xbet 로그인novative, fast-grow1xbet 로그인g health care company that commercializes Otsuka medic1xbet 로그인es 1xbet 로그인 Canada, with a focus on commitment to neuroscience, cardiovascular, and oncology. OCPI is dedicated to improv1xbet 로그인g patients' health and the quality of human life. OCPI is part of the Otsuka Group, and was established 1xbet 로그인 2010, with headquarters 1xbet 로그인 Technoparc Montreal, 1xbet 로그인 Sa1xbet 로그인t-Laurent, Quebec.

About Lundbeck 1xbet 로그인c.

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