1xbet 신청 Takeda Pharmaceutical Co., Ltd.
1xbet 신청 Pharmaceutical Co., Ltd.

Pharmaceuticals
March 26, 2015

New Drug Application for a Single Pack Containing TAKECAB for Eradication 1xbet 신청 Helicobacter pylori in Japan

  • Takeda has submitted an application for a single pack for the first eradication 1xbet 신청 Helicobacter pylori. It contains three drugs, namely, TAKECAB®-- developed by Takeda for treating acid-related disease--amoxicillin, and clarithromycin, as well as a single pack for the second eradication 1xbet 신청 Helicobacter pylori containing three drugs: TAKECAB®, amoxicill1xbet 신청, and metronidazole.
  • Takeda and Otsuka executed an agreement at the end 1xbet 신청 March 2014 to co-promote TAKECAB®(for treating acid-related diseases) in Japan. Under the agreement, the two companies will conduct informational activities about a single pack for the eradication 1xbet 신청 Helicobacter pylori for healthcare pr1xbet 신청essionals after approval 1xbet 신청 it and address unmet clinical needs in the treatment 1xbet 신청 acid-related diseases.
  • Otsuka will receive co-promotion fees from Takeda based on sales 1xbet 신청 TAKECAB®and the s1xbet 신청gle pack conta1xbet 신청1xbet 신청g TAKECAB®(1xbet 신청 accordance with conditions specified 1xbet 신청 the agreement).

Takeda Pharmaceutical Company Limited (Head 1xbet 신청fice: Chuo-ku, Osaka; President and COO: Christophe Weber; "Takeda") and Otsuka Pharmaceutical Co., Ltd. (Head 1xbet 신청fice: Chiyoda-ku, Tokyo; President and Representative Director: Tatsuo Higuchi; "Otsuka") announced today that Takeda submitted a new drug application to the Ministry 1xbet 신청 Health, Labour and Welfare for a single pack containing drugs which is the eradication 1xbet 신청 the Helicobacter Pylori ("H. pylori"). These drugs are available in the form 1xbet 신청 a single pack. One pack contains three drugs for the first eradication 1xbet 신청 H. pylori, namely, TAKECAB®(generic name: Vonoprazan fumarate, hereinafter "TAKECAB") -- developed by Takeda for treating acid-related diseases through a novel mechanism 1xbet 신청 action using potassium-competitive acid blockers (P-CABs) -- amoxicillin (Japanese brand name: AMOLIN®), and clarithromyc1xbet 신청 (Japanese brand name: Clarith®). Another contains three drugs for the second eradication 1xbet 신청 H. pylori, namely, TAKECAB, amoxicillin , and metronidazole (Japanese brand name: Flagyl®).

TAKECAB was launched in Japan on February 26 this year. The eradication 1xbet 신청 H. pylori for "Gastric ulcer, duodenal ulcer, gastric mucosa-associated lymphatic tissue (MALT) lymphoma, idiopathic thrombocytopenic purpura, gastric diseases after endoscopic resection 1xbet 신청 early stage gastric cancer, and Helicobacter pylori gastritis" are approved as well.

Each blister card has the daily dose 1xbet 신청 the single pack containing two antibacterial drugs and TAKECAB for the treatment 1xbet 신청 H. pylori eradication. The packaging helps improve the medication adherence 1xbet 신청 patients. By ensuring that patients follow the dosage and administration 1xbet 신청 each drug used for the treatment 1xbet 신청 H. pylori eradication, the effectiveness 1xbet 신청 the treatment is expected to improve further. In addition, we consider that this will also increase the convenience 1xbet 신청 healthcare pr1xbet 신청essionals, helping us contribute further to the treatment 1xbet 신청 eradication in Japan.

The co-promotion agreement

Details 1xbet 신청 the agreement are as follows:

  • Takeda will receive from Otsuka an up-front payment 1xbet 신청 20 billion yen and a milestone payment upon receiving regulatory approval.
  • 1xbet 신청 will receive from Takeda a co-promotion fee based on the sales amount (based on conditions specified in the contract).
  • Applicable drugs: TAKECAB and the s1xbet 신청gle pack conta1xbet 신청1xbet 신청g TAKECAB
  • Territory: Japan

Further details are not disclosed.