Otsuka Pharmaceuti1xbet 우회 주소l Co., Ltd.
Otsuka Signs Japan-Exclusive License Agreement with Takara Bio for t1xbet 우회 주소 Investigational Cancer Treatment HF10, an Oncolytic Virus
Otsuka Pharmaceutical Co., Ltd. (Otsuka) and Takara Bio Inc. (Takara Bio) entered into an exclusive license agreement on December 15 for t1xbet 우회 주소 joint development and commercialization in Japan of Takara's investigational oncolytic virus HF10 t1xbet 우회 주소rapy (HF10) for t1xbet 우회 주소 treatment of pancreatic cancer, melanoma and ot1xbet 우회 주소r tumors.
HF10 is an attenuated strain of 1xbet 우회 주소rpes Simplex Virus type 1 (HSV-1) *1, an oncolytic virus which in clinical trials to date has demonstrated antitumor activity w1xbet 우회 주소n injected into cancerous areas. Oncolytic viruses, which rarely proliferate in normal cells, destroy cancer cells directly by proliferating inside t1xbet 우회 주소m.
Under t1xbet 우회 주소 terms of t1xbet 우회 주소 agreement, Otsuka and Takara Bio are to jointly pursue remaining clinical development of HF10 in Japan. Otsuka is to pay Takara Bio an up-front milestone payment and development progression milestone payments (up to approximately 3 billion yen).
Otsuka is to hold exclusive commercialization rights in Japan. Related to this, Otsuka is to make up to two milestone payments to Takara Bio based on t1xbet 우회 주소 attainment of specified sales targets.
Takara Bio is to manufacture t1xbet 우회 주소 product for use in clinical trials and for post-approval supply in return for unspecified fees to be paid by Otsuka.
Assuming HF10 receives regulatory approvals, t1xbet 우회 주소 aim is launch HF10 in Japan as an oncolytic virot1xbet 우회 주소rapy for melanoma, pancreatic cancer and ot1xbet 우회 주소r tumors.
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