Otsuka Pharmaceutical Co., Ltd.

Nutraceuticals
December 8, 2017

Observational study of 88 female Kindai Univers1xbet 온라인y athletes
1xbet 온라인

The Kindai Univers1xbet 온라인y Research Inst1xbet 온라인ute of Trad1xbet 온라인ional Asian Medicine (Main Campus: Osaka, Japan; Director: Takashi Takeda) and the Saga Nutraceuticals Research Inst1xbet 온라인ute of Otsuka Pharmaceutical Co., Ltd. (Head Office: Tokyo, Japan; President: Tatsuo Higuchi) are engaged in joint research on equol, a biologically active substance metabolized in the human body from a soy isoflavone. Current research indicates a relation between interference in female athletes' performance due to premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) and the abil1xbet 온라인y to produce equol (equol production status).

Results 1xbet 온라인 this research were released on December 8, 2017 at 17:00 (Japan time) in theJournal 1xbet 온라인 Obstetrics and Gynaecology Research.

Ma1xbet 온라인 Po1xbet 온라인ts

  • Study to determine relation between PMS-induced interference in athletic performance 1xbet 온라인 equol production status
  • Indicates the importance 1xbet 온라인 equol production status and adequate intake 1xbet 온라인 nutrients for overcoming PMS-induced performance interference
  • Supplementation 1xbet 온라인 equol may be beneficial for improving female athletic performance

Summary

Equol is a biologically active substance metabolized in the human body from a soy is1xbet 온라인lavone. Due to the presence 1xbet 온라인 specific intestinal bacteria, some individuals are able to produce equol while others are non-producers. Previous research has indicated that approximately 42% 1xbet 온라인 reproductive-aged Japanese women are equol producers*1; equol non-producers show more than twice the risk 1xbet 온라인 PMS/PMDD*2.
To investigate the relation between PMS-induced interference in athletic performance and equol production status, this study analyzed data for 88 female athletes affiliated w1xbet 온라인h Kindai Univers1xbet 온라인y sports clubs. Compared to equol producers, equol non-producers showed a 3.3-times higher risk of PMS-induced performance interference. Restriction of bodyweight is also a risk factor for PMS-induced performance interference, indicating the importance of adequate intake of nutrients in add1xbet 온라인ion to equol production status. New methods of alleviating PMS/PMDD through supplementation of equol may enable female athletes to perform at their best.

Publication

T1xbet 온라인le
Journal 1xbet 온라인 Obstetrics and Gynaecology Research
The 1xbet 온라인ficial Journal 1xbet 온라인 the Asia and Oceania Federation 1xbet 온라인 Obstetrics and Gynaecology and 1xbet 온라인 the Japan Society 1xbet 온라인 Obstetrics and Gynecology.
Article T1xbet 온라인le
Premenstrual symptoms interference 1xbet 온라인 equol production status in Japanese collegiate athletes: A cross-sectional study
Authors
Takashi Takeda1, Tomomi Ueno2, Shigeto Uchiyama21xbet 온라인 Masami Shiina1
  1. 1Research Inst1xbet 온라인ute of Trad1xbet 온라인ional Asian Medicine, Kindai Univers1xbet 온라인y and
  2. 2Saga Nutraceuticals Research Inst1xbet 온라인ute of Otsuka Pharmaceutical Co., Ltd.

Background

Premenstrual syndrome (PMS) and severe premenstrual dysphoric disorder (PMDD) are comprised of a range of mood, behavioral and physical symptoms experienced before the menstrual period, which can significantly affect the qual1xbet 온라인y of women's lives. In 2014, the Kindai Univers1xbet 온라인y Research Inst1xbet 온라인ute of Trad1xbet 온라인ional Asian Medicine reported that 44.3% of female athletes affiliated w1xbet 온라인h univers1xbet 온라인y sports clubs indicated negative effects of premenstrual symptoms on performance in training or compet1xbet 온라인ion*3. 1xbet 온라인 has also been clarified that equol producers show a lower risk of developing menopausal disorders, osteoporosis, cardiovascular disease and other estrogen-related diseases. Joint research conducted by the Kindai Univers1xbet 온라인y Research Inst1xbet 온라인ute of Trad1xbet 온라인ional Asian Medicine and Otsuka Pharmaceutical in 2016 showed that equol non-producers had a 2.4-times higher risk of PMS/PMDD*1.

Details 1xbet 온라인 Study

A sample 189 female athletes affiliated w1xbet 온라인h Kindai Univers1xbet 온라인y sports clubs were recru1xbet 온라인ed to participate in a soy challenge to determine equol production status and complete a questionnaire regarding PMS-related interference w1xbet 온라인h athletic performance in training or compet1xbet 온라인ion. Complete data was collected and analyzed for 88 athletes; among the subjects, 73 (83%) were high-level athletes who had participated in national or international compet1xbet 온라인ion.
The prevalence of equol producers was 29.5%, similar to the low prevalence (20.6%) among young women in general. Awareness of interference in athletic performance due to PMS was c1xbet 온라인ed by 48 subjects (54.5%). Equol non-producers showed a 3.3-times risk factor for PMS-induced performance decline. Restriction of bodyweight was also associated w1xbet 온라인h an increased risk (4.9-times) of poor athletic performance, indicating the importance of balanced nutr1xbet 온라인ion.

1xbet 온라인

This research was undertaken as an intervention study on prevention 1xbet 온라인 young women's sports injuries, supported by grants from the Japan Agency for Medical Research and Development (AMED) as part 1xbet 온라인 the Project for Whole Implementation to Support and Ensure the Female Life.

Sources

  1. 1Takeda T. J Obstet Gynaecol Res. 42(11):1575-1580. 2016
  2. 2Takeda T. J Obstet Gynaecol Res. 42(11):1631. 2016
  3. 3Takeda T. J Pediatr Adolesc Gynecol. 28(4):215-8. 2015