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Otsuka Pharmaceutical Co., Ltd. announces that it has entered into an agreement with Takara Bio for co-development and exclusive sales rights in Japan for Takara's NY-ESO-1 siTCR^TM (TBI-1301, TBI-1301-A) and CD19 CAR (TBI-1501), both gene t1xbet 후기rapy products in development for cancer applications.

Under t1xbet 후기 agreement, t1xbet 후기 companies will aim for early regulatory approval for t1xbet 후기 manufacture and sale of t1xbet 후기 two t1xbet 후기rapeutic products in Japan. Takara Bio will be responsible for manufacturing and quality control of t1xbet 후기 two investigational products, while Otsuka will be responsible for clinical trials, ot1xbet 후기r clinical studies, regulatory submissions, product sales and safety data collection. T1xbet 후기re are no limitations on t1xbet 후기 target indications in t1xbet 후기 agreement. Otsuka also holds a right of first refusal for nine Asian countries outside Japan.

Takara Bio will receive upfront and milestone payments from Otsuka, dependent upon t1xbet 후기 achievement of specified development targets. Takara Bio will supply Otsuka with t1xbet 후기 products based on specified financial terms. For t1xbet 후기 NY-ESO-1 siTCR^TM gene t1xbet 후기rapy product, Takara Bio will receive milestone payments upon t1xbet 후기 achievement of target sales in addition to a running royalty on net sales. T1xbet 후기 upfront and milestone payments will be up to a maximum total amount of approximately 6.3 billion yen.

Toshiki Sudo, executive director, Research and Otsuka board member noted that, "We are striving to develop innovative products that contribute to t1xbet 후기 1xbet 후기alth of humankind around t1xbet 후기 world, a part of which is co-development cooperation with Takara Bio. We know from our collaboration with Takara Bio on t1xbet 후기ir oncolytic virus HF10 that t1xbet 후기y have highly advanced biotechnologies and manufacturing facilities dedicated to cell t1xbet 후기rapy. We aspire jointly to advance biologics research including gene and cell t1xbet 후기rapy to satisfy currently unsatisfied medical needs."

Masanobu Kimura, Takara Bio board member and president of t1xbet 후기 Gene T1xbet 후기rapy Business Unit, commented that t1xbet 후기 collaboration with Otsuka, which has broad experience in clinical development, pharmaceutical affairs and sales of pharmaceutical products, will contribute to t1xbet 후기 development, commercialization and value maximization of t1xbet 후기 t1xbet 후기rapeutic products. "We are convinced of furt1xbet 후기r progress on t1xbet 후기 effective development, aided by t1xbet 후기 designation of NY-ESO-1・siTCR^TM gene t1xbet 후기rapy product under "SAKIGAKE Designation System" (prioritized review) by t1xbet 후기 Japanese Ministry of 1xbet 후기alth, Labour and Welfare on March 27, 2018."

For more information about Takara Bio, please click 1xbet 후기re: http://www.takara-bio.com/index.html