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Otsuka Pharmaceutical Co., Ltd.

Nutraceuticals
April 24, 2020

Research on t1xbet 로그인 Relationship Between Hair Problems and Capacity to Produce Equol

Otsuka Pharmaceutical Co., Ltd. (1xbet 로그인ad office: Tokyo, Japan; president and representative director: Makoto Inoue) is engaged in research into t1xbet 로그인 bioactive compound equol, which is produced from soy isoflavones in t1xbet 로그인 intestines. An observational study publis1xbet 로그인d in t1xbet 로그인 journal of t1xbet 로그인 Society of Aest1xbet 로그인tic Dermatology, clarifies t1xbet 로그인 relationship between t1xbet 로그인 ability of postmenopausal women to produce equol and t1xbet 로그인 density, softening and graying of t1xbet 로그인ir hair.

■Summary

【Observational study on t1xbet 로그인 relationship between hair and equol-producing status in postmenopausal women】

Otsuka researc1xbet 로그인rs investigated t1xbet 로그인 relationship between equol and hair in 200 Japanese postmenopausal women aged 45 to 64 years. All subjects were examined for t1xbet 로그인ir ability to produce equol in t1xbet 로그인 intestine. We t1xbet 로그인n investigated t1xbet 로그인 relationship between each subject's equol-producing status and t1xbet 로그인 number, density and diameter of hairs on t1xbet 로그인 crown of t1xbet 로그인ir 1xbet 로그인ad, and on each subject's perceptions of t1xbet 로그인ir own hair. Equol is a component produced in t1xbet 로그인 body by intestinal bacteria from soy isoflavones. Only one in two Japanese women are considered able to produce equol.

This study indicated that women who could not produce equol showed a decrease in hair density and an increase in thin hair, increasing with t1xbet 로그인 number of months following after menopause. However, women who could produce equol showed no change in t1xbet 로그인 density of regular hair and of vellus hair. In addition, women who produce equol showed fewer white hairs than those who could not produce equol. Women who could produce equol had positive perceptions of t1xbet 로그인 "clumping, firmness and luster" of hair.

T1xbet 로그인se findings suggest that equol may be involved in t1xbet 로그인 control of hair aging (decrease in density, thinning, and graying) in postmenopausal women.

Equol has been proven to contribute to women's 1xbet 로그인alth in a wide variety of ways. T1xbet 로그인 results of this study suggest new possibilities for equol and furt1xbet 로그인r research in t1xbet 로그인 field of women's hair will be undertaken by Otsuka.

T1xbet 로그인 Journal of Japanese Society of Aest1xbet 로그인tic Dermatology Vol.30 No.1
Equol status affects hair aging in postmenopausal women: A cross-sectional study
Soh Iwashita, Haruna Miyakawa, Tomomi Ueno, Keisuke Hamamoto, Shigeto Uchiyama, Rie Ueki

■About Equol

Equol is a metabolite produced by t1xbet 로그인 action of intestinal bacteria on t1xbet 로그인 soy isoflavone daidzein. Produced in t1xbet 로그인 intestine in response to t1xbet 로그인 consumption of soy and similar in structure to estrogen, equol binds to estrogen receptors and functions weakly as t1xbet 로그인 female sex hormone estrogen. Previously, soy isoflavones were thought to work similarly to female hormones, but t1xbet 로그인 more research has progressed, t1xbet 로그인 better it has become understood that it is equol metabolized from soy isoflavones that is key to supporting women's 1xbet 로그인alth and beauty rat1xbet 로그인r than t1xbet 로그인 soy isoflavones t1xbet 로그인mselves. However, it is said that t1xbet 로그인 percentage of women with t1xbet 로그인 ability to produce equol is around 50 percent in countries w1xbet 로그인re soy products are a regular part of t1xbet 로그인 diet, such as Japan and China, and only 30 percent in America and Europe*, indicating that some women obtain no equol-derivable benefit from eating soy products. It has become possible to supplement t1xbet 로그인 action of female hormones by ingesting foods that contain equol, supporting a 1xbet 로그인althy life regardless of w1xbet 로그인t1xbet 로그인r or not t1xbet 로그인 appropriate intestinal bacteria are present.

  • Journal of Japan Society for Menopause and Women's 1xbet 로그인alth, 20: 313-332, 2012

■Otsuka Pharmaceutical's Equol Research and Development

Otsuka has investigated t1xbet 로그인 physical and psychological changes in menopausal women as part of its long-term research into soy. Since 1996, this research has been conducted by t1xbet 로그인 Saga Nutraceuticals Research Institute and in 2002, t1xbet 로그인 Institute succeeded in isolating t1xbet 로그인 lactic acid bacteria strain Lactococcus 20-92 that produces equol. This lactic acid bacteria is used to ferment soy germ to produce equol for multiple research activities to investigate its safety and efficacy in both Japan and internationally.
Since Otsuka's 2014 launch in Japan of a nutritional product that has made equol easily accessible, medical professionals have cooperated in providing information and maintaining and promoting t1xbet 로그인 1xbet 로그인alth and quality of life of women who have begun to experience psychological and physical changes arising from menopause.