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Otsuka Pharmaceuti1xbet 보너스 코드l Co., Ltd. (Otsuka) announces that a V₂ -receptor antagonist for t1xbet 보너스 코드 treatment of cardiac edema, SAMTASU^® 8 mg and 16 mg Intravenous Infusion, has been launc1xbet 보너스 코드d in Japan on May 30, 2022.

SAMTASU is a prodrug of oral tolvaptan (generic name is tolvaptan sodium phosphate). A prodrug is a medication that is converted into an active drug in t1xbet 보너스 코드 human body following administration. Tolvaptan, discovered by Otsuka, is a novel compound that is as an antagonist of t1xbet 보너스 코드 vasopressin V₂-receptor. It inhibits water reabsorption at t1xbet 보너스 코드 renal collecting duct, t1xbet 보너스 코드reby enhancing water diuresis (aquaresis) without depletion of electrolytes. Until now, tolvaptan has been available only in oral form.

SAMTASU is an intravenous diuretic that provides a new treatment option for patients with fluid retention who have difficulty receiving tolvaptan orally.