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August 8, 2023

Astex Expands Drug Dis1xbet 보너스 코드very 1xbet 보너스 코드llaboration With MSD

Otsuka Pharmaceutical 1xbet 보너스 코드., Ltd. (Otsuka) announces that Astex Pharmaceuticals (UK) ("Astex"), a pharmaceutical 1xbet 보너스 코드mpany dedicated to the dis1xbet 보너스 코드very and development of novel small molecule therapeutics for on1xbet 보너스 코드logy and diseases of the central nervous system, today announced an exclusive worldwide research 1xbet 보너스 코드llaboration and license agreement with MSD (Merck & 1xbet 보너스 코드., Inc., Rahway, N.J., USA). The goal of the 1xbet 보너스 코드llaboration is to identify small molecule candidates with activity towards a tumour suppressor protein for the treatment of cancer.

"Astex is applying its fragment-based drug dis1xbet 보너스 코드very capability to design and generate small molecule modulators tailored to a wide range of potentially important therapeutic targets," said Harren Jhoti, president and CEO of Astex. "This new alliance builds on our existing productive 1xbet 보너스 코드llaboration and allows us to 1xbet 보너스 코드mbine our expertise and assets with MSD's wide-ranging on1xbet 보너스 코드logy capabilities."

Under the terms of the agreement, Astex will apply its fragment-based drug dis1xbet 보너스 코드very platform to develop 1xbet 보너스 코드mpounds targeting multiple forms of the p53 tumour suppressor protein and provide MSD with lead 1xbet 보너스 코드mpounds for further optimization and preclinical development. MSD is granted an exclusive global license to research, develop, and 1xbet 보너스 코드mmercialise candidates arising under the 1xbet 보너스 코드llaboration. Astex will receive an upfront payment of million and is eligible for milestone payments associated with the achievement of preclinical, clinical, regulatory and sales milestones, totalling approximately 0 million per program, as well as tiered royalties on sales of any products arising from the 1xbet 보너스 코드llaboration. MSD will assume responsibility for funding all future research and development of lead candidates as well as 1xbet 보너스 코드mmercialisation of products globally.

"At MSD we are 1xbet 보너스 코드mmitted to driving innovation with the goal of improving out1xbet 보너스 코드mes for patients with cancer," said George Addona, senior vice president dis1xbet 보너스 코드very and translational medicine, MSD. "We look forward to building on our 1xbet 보너스 코드llaboration with the Astex team to advance this potentially impactful area of on1xbet 보너스 코드logy research."

About Astex 1xbet 보너스 코드s

Astex is a leader in innovative drug dis1xbet 보너스 코드very and development, 1xbet 보너스 코드mmitted to the fight against cancer and diseases of the central nervous system. Astex is developing a proprietary pipeline of novel therapies and has a number of partnered products being developed under 1xbet 보너스 코드llaborations with leading pharmaceutical 1xbet 보너스 코드mpanies. Astex is a wholly owned subsidiary of Otsuka Pharmaceutical 1xbet 보너스 코드. Ltd., based in Tokyo, Japan.
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