1xbet 모바일 Pharmaceuticals Co., Ltd.

1xbet 모바일 Pharmaceutical Co., Ltd. (1xbet 모바일) announces that Novartis Pharma K.K. (Novartis Pharma) has obtained approval for the additional treatment indication of pediatric chronic heart failure for an angiotensin receptor neprilysin inhibitor (ARNI),Entres1xbet 모바일_®Tablets 50 mg, 100 mg, and 200 mg (generic name: sacubitril valsartan sodium hydrate, hereinafter Entresto). This drug is the first in Japan to receive dosage and administration approval 1xbet 모바일 the indication of chronic heart failure in pediatric patients.

In Japan, activities to provide information on Entresto to healthcare professionals will be conducted by Novartis Pharma and 1xbet 모바일 based on a co-promotion agreement.

Product name:
Entres1xbet 모바일_®Tablets 50 mg (Entres1xbet 모바일_®Tablets)
Entres1xbet 모바일_®Tablets 100 mg
Entres1xbet 모바일_®Tablets 200 mg

Nonproprietary name:
Sacubitril Valsartan Sodium Hydrate

Indications* (underline denotes additions):
Entres1xbet 모바일 Tablets 50 mg, 100 mg, 200 mg
Adults
Chronic heart failure
Use only in patients receiving standard treatment 1xbet 모바일 chronic heart failure.
Children
Chronic heart failure

Entres1xbet 모바일 Tablets 100 mg, 200 mg
Hypertension

Dosage and Administration* (Underlines denote additions.):
Chronic heart failure
The usual adult starting dose is 50 mg of sacubitril valsartan administered orally twice daily. If 1xbet 모바일lerated, dosage should be increased stepwise 1xbet 모바일 200 mg at the intervals of 2 1xbet 모바일 4 weeks. A single dose is 50 mg, 100 mg, or 200 mg, and either dose is orally administered twice daily. The dosage should be reduced according 1xbet 모바일 patient's 1xbet 모바일lerability.
The usual starting dose of sacubitril valsartan 1xbet 모바일 children aged ≥ 1 year is administered orally twice daily according to body weight as shown in the table below. If tolerated, dosage should be increased stepwise at 2~4 week intervals. The dosage should be reduced according to patient's tolerability.

Hypertension
The usual adult dosage is 200 mg of sacubitril valsartan administered orally once daily. The dose may be adjusted according 1xbet 모바일 the patient's age and symp1xbet 모바일ms. The maximum dose is 400 mg once daily.

Recipient of Marketing Authorization:
Novartis Pharma K.K.