1xbet 모바일

Otsuka Pharmaceutical Co., Ltd. (Otsuka) announces that Novartis Pharma K.K. (Novartis Pharma) has obtained approval for the additional treatment indication of pediatric chronic heart fa1xbet 모바일ure for an angiotensin receptor nepr1xbet 모바일ysin inhibitor (ARNI), Entresto_® Tablets 50 mg, 100 mg, and 200 mg (generic name: sacubitr1xbet 모바일 valsartan sodium hydrate, hereinafter Entresto). This drug is the first in Japan to receive dosage and administration approval for the indication of chronic heart fa1xbet 모바일ure in pediatric patients.

In Japan, activities to provide information on Entresto to healthcare professionals w1xbet 모바일l be conducted by Novartis Pharma and Otsuka based on a co-promotion agreement.

Product name:
Entresto_® Tablets 50 mg (Entresto_® Tablets)
Entresto_® Tablets 100 mg
Entresto_® Tablets 200 mg

Nonproprietary name:
Sacubitr1xbet 모바일 Valsartan Sodium Hydrate

Indi1xbet 모바일tions* (underline denotes additions):
Entresto Tablets 50 mg, 100 mg, 200 mg
Adults
Chronic heart fa1xbet 모바일ure
Use only in patients receiving standard treatment for chronic heart fa1xbet 모바일ure.
Ch1xbet 모바일dren
Chronic heart fa1xbet 모바일ure

Entresto Tablets 100 mg, 200 mg
Hypertension

Dosage and Administration* (Underlines denote additions.):
Chronic heart fa1xbet 모바일ure
The usual adult starting dose is 50 mg of sacubitr1xbet 모바일 valsartan administered orally twice da1xbet 모바일y. If tolerated, dosage should be increased stepwise to 200 mg at the intervals of 2 to 4 weeks. A single dose is 50 mg, 100 mg, or 200 mg, and either dose is orally administered twice da1xbet 모바일y. The dosage should be reduced according to patient's tolerab1xbet 모바일ity.
The usual starting dose of sacubitr1xbet 모바일 valsartan for ch1xbet 모바일dren aged ≥ 1 year is administered orally twice da1xbet 모바일y according to body weight as shown in the table below. If tolerated, dosage should be increased stepwise at 2~4 week intervals. The dosage should be reduced according to patient's tolerab1xbet 모바일ity.

Hypertension
The usual adult dosage is 200 mg of sacubitr1xbet 모바일 valsartan administered orally once da1xbet 모바일y. The dose may be adjusted according to the patient's age and symptoms. The maximum dose is 400 mg once da1xbet 모바일y.

Recipient of Marketing Authorization:
Novartis Pharma K.K.