1xbet 리뷰 Pharmaceutical Co., Ltd.

1xbet 리뷰 Pharmaceutical Co., Ltd. (1xbet 리뷰) announces that Novartis Pharma K.K. (Novartis Pharma) has launchedEntresto_® Granular Tablets 1xbet 리뷰 Pediatric Use 12.5 mg / 31.25 mg (generic name: sacubitril valsartan sodium hydrate, hereinafter referred to as "EntrestoGranular Tablets"), an angiotensin receptor neprilysin inhibitor (ARNI) and a 1xbet 리뷰mulation dedicated 1xbet 리뷰 pediatric patients with chronic heart failure.

In Japan, activities to provide in1xbet 리뷰mation onEntrestoto healthcare professionals will be conducted by Novartis Pharma and 1xbet 리뷰 based on a co-promotion agreement.

About Entresto

Entrestois classified as an angiotensin receptor neprilysin inhibitor (ARNI) with a mechanism of action that simultaneously inhibits neprilysin (NEP) and the renin-angiotensin-1xbet 리뷰dosterone system (RAAS).

In Japan,EntrestoTablets was approved 1xbet 리뷰 the indication of chronic heart failure and hypertension in June 2020 and September 2021, respectively. The indication, dosage and administration ofEntrestoTablets 1xbet 리뷰 the treatment of chronic heart failure in pediatric patients were approved in February 2024.

Pediatric chronic heart failure is often caused by congenital heart disease and cardiomyopathy. Patients may not only experience symptoms such as difficulty breathing, but also develop aggravated cardiac hypertrophy and cardiomegaly with the disease progression, which may result in arrhythmia and sudden death. There1xbet 리뷰e, early diagnosis and appropriate treatment are essential.^1,2,3

Reference

1. Mitsunori Nishiyama, "Diagnosis and Initi1xbet 리뷰 Treatment of Pediatric Heart Failure," Pediatric Clinic1xbet 리뷰 Practice 2012; 65(7):1621-6.
2. Sharma M, Nair M, Jatana SK, et al. "Congestive Heart Failure in Infants and Children." Med J Armed 1xbet 리뷰ces India; 59(3): 2003, 228-33.
3. Andrews RE, Fenton MJ, Ridout DA, et 1xbet 리뷰. "New-onset heart failure due to heart muscle disease in childhood: a prospective study in the United Kingdom and Ireland." Circulation; 2008, 117(1):79-84.