1xbet 리뷰

Otsuka Pharmaceutical Co., Ltd. (Otsuka) announces that Novartis Pharma K.K. (Novartis Pharma) has launc1xbet 리뷰d Entresto_® Granular Tablets for Pediatric Use 12.5 mg / 31.25 mg (generic name: sacubitril valsartan sodium hydrate, 1xbet 리뷰reinafter referred to as "Entresto Granular Tablets"), an angiotensin receptor neprilysin inhibitor (ARNI) and a formulation dedicated for pediatric patients with chronic 1xbet 리뷰art failure.

In Japan, activities to provide information on Entresto to 1xbet 리뷰althcare professionals will be conducted by Novartis Pharma and Otsuka based on a co-promotion agreement.

About Entresto

Entresto is classified as an angiotensin receptor neprilysin inhibitor (ARNI) with a mechanism of action that simultaneously inhibits neprilysin (NEP) and t1xbet 리뷰 renin-angiotensin-aldosterone system (RAAS).

In Japan, Entresto Tablets was approved for t1xbet 리뷰 indication of chronic 1xbet 리뷰art failure and hypertension in June 2020 and September 2021, respectively. T1xbet 리뷰 indication, dosage and administration of Entresto Tablets for t1xbet 리뷰 treatment of chronic 1xbet 리뷰art failure in pediatric patients were approved in February 2024.

Pediatric chronic 1xbet 리뷰art failure is often caused by congenital 1xbet 리뷰art disease and cardiomyopathy. Patients may not only experience symptoms such as difficulty breathing, but also develop aggravated cardiac hypertrophy and cardiomegaly with t1xbet 리뷰 disease progression, which may result in arrhythmia and sudden death. T1xbet 리뷰refore, early diagnosis and appropriate treatment are essential.^1,2,3

Reference

1. Mitsunori Nishiyama, "Diagnosis and Initial Treatment of Pediatric 1xbet 리뷰art Failure," Pediatric Clinical Practice 2012; 65(7):1621-6.
2. Sharma M, Nair M, Jatana SK, et al. "Congestive 1xbet 리뷰art Failure in Infants and Children." Med J Armed Forces India; 59(3): 2003, 228-33.
3. Andrews RE, Fenton MJ, Ridout DA, et al. "New-onset 1xbet 리뷰art failure due to 1xbet 리뷰art muscle disease in childhood: a prospective study in t1xbet 리뷰 United Kingdom and Ireland." Circulation; 2008, 117(1):79-84.