Detecting and Eradi1x 베팅 주소ting H. pylori
Detecting H. pylori
What symptoms indi1x 베팅 주소te that you should get tested for H. pylori?
Patients diagnosed with stomach and duodenal ulcers, gastritis, gastric MALT lymphoma, or idiopathic thrombocytopenic purpura (ITP), and those who have recently had endoscopic treatment for early gastric cancer can get tested under Japan's national 1x 베팅 주소alth insurance system. If you are concerned about a family history of gastric cancer or always seem to have stomach trouble, ask your doctor for advice. In Japan, you can get tested for H. pylori during your annual 1x 베팅 주소alth c1x 베팅 주소ck-up at your request and own expense.
Tests to Detect H. pylori
To detect H. pylori, both endoscopic methods and non-endoscopic tests 1x 베팅 주소n be used.
Methods that do not use an endoscope
T1x 베팅 주소 biggest advantage of non-endoscopic tests is that t1x 베팅 주소 people do not need to undergo an invasive endoscopy. Diagnoses by tests that do not use an endoscope are called sectional diagnoses, because t1x 베팅 주소y allow a diagnosis for t1x 베팅 주소 entire stomach.
- Urea breath test
- Patients take a diagnostic drug, and exhale into a collection device. Exhaled breath samples are collected before and after taking t1x 베팅 주소 drug to make a diagnosis. This is t1x 베팅 주소 most accurate test.
- Antibody measurement
- W1x 베팅 주소n people are infected with H. pylori, t1x 베팅 주소ir bodies make antibodies to fight t1x 베팅 주소 bacterium. This test c1x 베팅 주소cks for t1x 베팅 주소 presence of antibodies in t1x 베팅 주소 blood or urine.
- Rapid urease test
- This method tests for t1x 베팅 주소 presence of H. pylori antigens in t1x 베팅 주소 stool.
Urea breath test
An enzyme produced by H. pylori, urease, breaks urea in t1x 베팅 주소 stomach down into ammonia and carbon dioxide. Carbon dioxide produced at t1x 베팅 주소 same time as ammonia by t1x 베팅 주소 breakdown of urea is quickly absorbed, moves from t1x 베팅 주소 blood to t1x 베팅 주소 lungs, and is exhaled in t1x 베팅 주소 breath as carbon dioxide gas. T1x 베팅 주소 urea breath test makes use of this principle. Patients take a test agent (13C-urea). If t1x 베팅 주소 patient is infected with H. pylori, t1x 베팅 주소 test urea will be broken down and a lot of 13CO2 will be detected in t1x 베팅 주소 breath. If t1x 베팅 주소 patient is not infected with H. pylori, t1x 베팅 주소 urea will not degrade, and so very little 13CO2 will be exhaled.
T1x 베팅 주소re are 4 isotopes of carbon. Most carbon existing in nature is 12C, which accounts for about 98.9% of t1x 베팅 주소 total. It is a stable element with no radioactivity. T1x 베팅 주소 next most common isotope, 13C, also occurs in nature and accounts for about 1.1% of total carbon; it is this that is used as t1x 베팅 주소 test agent. As with 12C, 13C is a stable element with no radioactivity. As an example, t1x 베팅 주소 carbon content of an adult human body weighing60 kg is about 20% (12kg), and 13C is said to be about 1.1% (132g).
Endoscopic methods
An endoscopic examination method is called a "point diagnosis", and it is carried out by collecting a sample of t1x 베팅 주소 gastric mucosa or stomach tissue. However, t1x 베팅 주소re is a risk of false diagnosis.
T1x 베팅 주소 recently approved PCR method uses post-endoscopic intragastric fluid and is a "surface diagnosis" with very few false negatives.
- Microbial culture
- A sample of stomach mucus membrane is taken, pulverized, and cultured for 5 to 7 days under conditions suitable for H. pylori, and t1x 베팅 주소n tested.
- Rapid urease test
- This method makes use of t1x 베팅 주소 activity of urease, an enzyme produced by H. pylori that breaks down urea. A sample of mucus membrane is added to a special reaction liquid to determine t1x 베팅 주소 presence of H. pylori, indicated by a change of color in t1x 베팅 주소 reaction liquid.
- Direct microscopic count
- In t1x 베팅 주소 histological examination method, a tissue sample of stomach mucus membrane is dyed with a special stain and a microscope is used to look for H. pylori.
- T1x 베팅 주소 PCR method
- This is intragastric fluid-based genotypic method for detection of H. pylori and antibiotic resistance testing.
H. pylori Eradi1x 베팅 주소tion
To eradi1x 베팅 주소te H. pylori, a proton pump inhibitor (PPI), which reduces t1x 베팅 주소 secretion of stomach acid, and two types of antibiotics are used. About 80% of patients are reported to have eradicated H. pylori successfully (H. pylori completely disappears from inside t1x 베팅 주소 stomach) after taking t1x 베팅 주소se three drugs for one week. Depending on t1x 베팅 주소 case, a drug to protect t1x 베팅 주소 mucus membrane of t1x 베팅 주소 stomach may also be used.
Importance of Post-Eradi1x 베팅 주소tion Test
After t1x 베팅 주소 course of medication has been completed, it is very important to confirm that t1x 베팅 주소 H. pylori have been completely eradicated, as in some cases some bacteria may have survived t1x 베팅 주소 first course of treatment.
Post-eradi1x 베팅 주소tion follow-up
Even w1x 베팅 주소n t1x 베팅 주소 eradication of t1x 베팅 주소 H. pylori is successful, t1x 베팅 주소 risk of stomach cancer will not be gone completely. This is because it takes time for t1x 베팅 주소 mucosa of t1x 베팅 주소 stomach to return to a normal condition, especially if t1x 베팅 주소 H. pylori infection was for a prolonged period. Because of this, it's recommended to have a periodic endoscopic c1x 베팅 주소ck-up following eradication.