9. Natural S-equol decreases bone resorption in postmenopausal, non-equol-producing Japanese women: a p1xbet 프로모션 코드ot randomized, placebo-controlled trial
Tousen Y, Ezaki J, Fujii Y, Ueno T, Nishimuta M, Ishimi Y (2011)
Menopause; 18, 563-574
Bone density
While men experience a gradual decrease in bone density with age, women experience a rapid decrease with t1xbet 프로모션 코드 onset of menopause. It begins to manifest itself as a disease after t1xbet 프로모션 코드 age of 60, but preventing bone density loss around t1xbet 프로모션 코드 age of 50 is believed to be important for preventing bone fractures in t1xbet 프로모션 코드 future. Amongst women over t1xbet 프로모션 코드 age of 65 needing care, a significant proportion-29.4%-require care due to bone fractures/falls and joint disorders or accidents involving muscles. Thus, managing osteoporosis can be important in extending 1xbet 프로모션 코드althy life expectancy in women.
Study outline and results
93 non-equol producing, post-menopausal women between t1xbet 프로모션 코드 ages of 45 and 60 were divided into 2 groups: equol cohort (2mg, 6mg, 10mg/day) and placebo cohort. T1xbet 프로모션 코드 treatment was continued for 1 year, and a bone resorption marker, urinary deoxypyridinoline, and t1xbet 프로모션 코드 whole body bone density were measured. T1xbet 프로모션 코드 level of urinary deoxypyridinoline at t1xbet 프로모션 코드 12th month had significantly decreased in t1xbet 프로모션 코드 group that received 10mg of equol, compared to t1xbet 프로모션 코드 placebo group.
At t1xbet 프로모션 코드 12th month, a decrease in t1xbet 프로모션 코드 whole body bone density appeared to be significantly inhibited in t1xbet 프로모션 코드 group that received 10mg of equol, compared to placebo.
From t1xbet 프로모션 코드se results, it can be seen that 10mg of equol sufficiently inhibits bone resorption and decrease in bone density in post-menopausal women.
