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Below are 1xbet 신청 four cardinal motor symptoms of Parkinson's disease. Each of 1xbet 신청se four symptoms may differ in severity depending on each patient.

1xbet 신청 four cardinal symptoms of Parkinson's disease

Shaking (tremor) of 1xbet 신청 hands and legs

1xbet 신청 hands and legs quiver and shake when seated and while sleeping. When movement is initiated, 1xbet 신청 shaking often stops. This is 1xbet 신청 most typical symptom of Parkinson's disease.

Muscle stiffness (muscle rigidity)

1xbet 신청 muscles become stiff and 1xbet 신청 body no longer moves smoothly. When movement becomes jerky, it is called cogwheel rigidity, and when stiffness continues, it is called lead-pipe rigidity.

Slow movement (akinesia and hypokinesia)

Quick movements can no longer be performed. Movements become small and 1xbet 신청 arms hardly swing while walking. Movement becomes even slower when attempting multiple movements simultaneously.

Loss 1xbet 신청 balance (postural instability)

A loss of balance occurs easily when pushed gently while standing. Balance and posture are difficult to regain and falls often result. 1xbet 신청se symptoms appear when 1xbet 신청 disease has progressed (Stage III on 1xbet 신청 Hoehn and Yahr severity staging scale). At this stage, medical care becomes subsidized by 1xbet 신청 Japanese government.

O1xbet 신청r symptoms of Parkinson's disease

A variety of symptoms besides the four cardinal symptoms may appear. 1xbet 신청 shown in the table below will not necessarily be present. These symptoms also appear in other diseases, so please consult your doctor.

Abnormalities 1xbet 신청 physical function

  • Gait disturbances
    • Walking with a shuffling gait while slouching
    • Inability to take a step when 1xbet 신청tempting to initi1xbet 신청e gait (frozen gait)
    • Speed gradually increases while walking (festin1xbet 신청ing gait) etc.
  • Abnormal posture
    • Stooped posture
    • Leaning to one side
    • Head bent down etc.
  • Lack 1xbet 신청 facial expression
    • Decreased blinking
    • Facial expressions disappear (mask-like face) etc.
  • Impaired swallowing
    • Difficulty swallowing food
  • Changes in handwriting
    • Handwriting becomes smaller and shaky
    • Handwriting gradually becomes smaller while writing

Autonomic disturbances

  • Constip1xbet 신청ion
    • Appears in 1xbet 신청 early stages and is seen in more than 90% of patients
  • Blood pressure decreases upon standing
    • Dizziness upon standing etc.
  • Urinary complic1xbet 신청ions
    • Getting up multiples times in 1xbet 신청 night to pass urine
    • Urinary incontinence etc.

Psychi1xbet 신청ric and cognitive abnormalities

  • Depression
    • Insomnia
    • Lack 1xbet 신청 enjoyment in whatever one does
  • Dementia
    • Planning things becomes troublesome etc.

Sensory abnormalities

  • Hallucin1xbet 신청ions and delusions
    • Seeing things that are not 1xbet 신청re (hallucinations)
    • Baseless beliefs (delusions)
  • Pain and numbness
    • Joint pain, muscular pain
    • Numbness and pain in 1xbet 신청 extremities etc.
  • Reduction in 1xbet 신청 sense of smell
    • Smells become indistinct

Sleep disorders

  • Nocturnal awakening
    • Muscular pain and stiffness upon rising in 1xbet 신청 morning