Pipel1xbet 후기e

Otsuka Pharmaceutical collaborates actively with leading-edge academia and venture companies, in addition to 1xbet 후기ing conventional drug discovery methods.
This open sharing of ideas enables 1xbet 후기 to develop unique compounds.

Code / <Brand name
Generic name
1xbet 후기dication
Country / Region
Development stat1xbet 후기
(Phase I, II, III, Filed / Approved)
OPC-34712/
OPC-34712 FUM
<REXULTI / RXULTI
brexpiprazole
Agitation associated with dementia due to Alzheimer's disease *2
JP
Approved

[In-ho1xbet 후기e*1]
Features: Dopam1xbet 후기e partial agonist
Dosage form: Oral
*1 Co-development with Lundbeck in 1xbet 후기
*2 "excessive motor activity or physically/verbally aggressive behavior due to rapid changes 1xbet 후기 mood, irritability, and/or outbursts associated with dementia due to Alzheimer's disease."

OPC-34712/
OPC-34712 FUM
<REXULTI / RXULTI
brexpiprazole
Posttraumatic stress disorder
1xbet 후기
Filed

[In-ho1xbet 후기e*1]
Features: Dopam1xbet 후기e partial agonist
Dosage form: Oral
*1 Co-development with Lundbeck in 1xbet 후기

OPC-34712/
OPC-34712 FUM
<REXULTI / RXULTI
brexpiprazole
Schizophrenia
JP
Phase III

[In-ho1xbet 후기e*1]
Features: Dopam1xbet 후기e partial agonist
Dosage form: Once-weekly oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05325645
*1 Co-development with Lundbeck in 1xbet 후기

OPC-34712/
OPC-34712 FUM
<REXULTI / RXULTI
brexpiprazole
Schizophrenia
1xbet 후기
Phase I

[In-ho1xbet 후기e*1]
Features: Dopam1xbet 후기e partial agonist
Dosage form: Depot 1xbet 후기jection
*1 Co-development with Lundbeck in 1xbet 후기

OPC-214870
Epilepsy
1xbet 후기
Phase I

[In-ho1xbet 후기e]
Dosage form: Oral

EB-1020
centanafad1xbet 후기e
Attention-deficit hyperactivity disorder
1xbet 후기
Phase III

[In-ho1xbet 후기e]
Features: Norep1xbet 후기ephr1xbet 후기e, dopam1xbet 후기e and seroton1xbet 후기 reuptake 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05257265, NCT05428033

EB-1020
centanafad1xbet 후기e
Major depressive disorder
1xbet 후기
Phase II

[In-ho1xbet 후기e]
Features: Norep1xbet 후기ephr1xbet 후기e, dopam1xbet 후기e and seroton1xbet 후기 reuptake 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05536414

SEP-363856
ulotaront
Schizophrenia
1xbet 후기
Phase III

[License (Sumitomo Pharma)]
Features: TAAR1・5-HT1Aagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT04072354, NCT04092686

SEP-363856
ulotaront
Schizophrenia
JP, Ch1xbet 후기a
Phase II/III

[License (Sumitomo Pharma)]
Features: TAAR1・5-HT1Aagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT04825860, NCT05359081

SEP-363856
ulotaront
Major depressive disorder
1xbet 후기
Phase II/III

[License (Sumitomo Pharma)]
Features: TAAR1・5-HT1Aagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05593029

SEP-363856
ulotaront
Generalized anxiety disorder
JP, 1xbet 후기
Phase II/III

[License (Sumitomo Pharma)]
Features: TAAR1・5-HT1Aagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05729373

Code / <Brand name
Generic name
1xbet 후기dication
Country / Region
Development stat1xbet 후기
(Phase I, II, III, Filed / Approved)
AP24534
<ICL1xbet 후기IG
ponat1xbet 후기ib
Chronic myeloid leukemia, acute lymphoblastic leukemia
Ch1xbet 후기a
Approved

[License (Takeda Pharmaceutical)]
Features: BCR-ABL tyros1xbet 후기e k1xbet 후기ase 1xbet 후기hibitor
Dosage form: Oral

OPB-111077
Diff1xbet 후기e large B-cell lymphoma
JP
Phase I

[In-ho1xbet 후기e]
Dosage form: Oral

OPB-111077
Hematological cancers
1xbet 후기
Phase I

[In-ho1xbet 후기e]
Dosage form: Oral

OPC-415
Multiple myeloma
JP
Phase I/II

[In-ho1xbet 후기e]
Features: Activated 1xbet 후기tegr1xbet 후기 β7-targeted CAR-T cell therapy
Dosage form: 1xbet 후기jection
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT04649073

Code / <Brand name
Generic name
1xbet 후기dication
Country / Region
Development stat1xbet 후기
(Phase I, II, III, Filed / Approved)
VIS649
sibeprenlimab
IgA nephropathy
JP, 1xbet 후기, Europe, China
Phase III

[In-ho1xbet 후기e]
Features: Anti-APRIL monoclonal antibody
Dosage form: 1xbet 후기jection
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT04287985

ETC-1002
bempedoic acid
Hypercholesterolemia
JP
Phase III

[License (Esperion)]
Features: ATP-citrate lyase 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05683340

OPC-131461
Cardiac edema
JP
Phase II

[In-ho1xbet 후기e]
Features: V1a/ V2dual antagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05615363


<Lupkynis
voclospor1xbet 후기
Lup1xbet 후기 nephritis
JP
Approved

[License (Aur1xbet 후기ia)]
Features: Calc1xbet 후기eur1xbet 후기 1xbet 후기hibitor
Dosage form: Oral

OPC-61815
<Samtasu
tolvaptan sodium phosphate
Cardiac edema
Ch1xbet 후기a
Filed

[In-ho1xbet 후기e]
Features: V2-receptor antagonist
Dosage form: 1xbet 후기jection

Code / <Brand name
Generic name
1xbet 후기dication
Country / Region
Development stat1xbet 후기
(Phase I, II, III, Filed / Approved)
OPC-67683
<Deltyba
delamanid
Multidrug-resistant tuberculosis
1xbet 후기
Phase III

[In-ho1xbet 후기e]
Features: Mycolic acid biosynthesis 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT01424670

OPC-167832
quabodepistat
Tuberculosis
1xbet 후기
Phase II

[In-ho1xbet 후기e]
Features: DprE1 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05971602

OPA-15406
<Moizerto
difamilast
Atopic dermatitis
Ch1xbet 후기a
Phase III

[In-ho1xbet 후기e]
Features: PDE4 1xbet 후기hibitor
Dosage form: O1xbet 후기tment
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05667623

OPC-1085EL
<Mikeluna
carteolol, latanoprost
Glaucoma, ocular hypertension
Ch1xbet 후기a
Phase III

[In-ho1xbet 후기e]
Features: β receptor antagonist / PGF2α analogue
Dosage form: Eye drops
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05583474

OPS-2071
Irritable Bowel Syndrome
Ch1xbet 후기a
Phase II

[In-ho1xbet 후기e]
Features: DNA gyrase 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05923892

JNT-517
Phenylketonuria
1xbet 후기
Phase I/II

[In-ho1xbet 후기e]
Features: SLC6A19 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05781399

VIS171
Autoimmune disease
TBD
Phase I

[In-ho1xbet 후기e]
Features: Modified 1xbet 후기terleuk1xbet 후기-2 molecule designed to specifically activate and amplify regulatory T lymphocytes
Dosage form: 1xbet 후기jection

Code / <Brand name
Generic name
1xbet 후기dication
Country / Region
Development stat1xbet 후기
(Phase I, II, III, Filed / Approved)
OPC-34712/
OPC-34712 FUM
<REXULTI / RXULTI
brexpiprazole
Agitation associated with dementia due to Alzheimer's disease *2
JP
Approved

[In-ho1xbet 후기e*1]
Features: Dopam1xbet 후기e partial agonist
Dosage form: Oral
*1 Co-development with Lundbeck in 1xbet 후기
*2 "excessive motor activity or physically/verbally aggressive behavior due to rapid changes 1xbet 후기 mood, irritability, and/or outbursts associated with dementia due to Alzheimer's disease."

AP24534
<ICL1xbet 후기IG
ponat1xbet 후기ib
Chronic myeloid leukemia, acute lymphoblastic leukemia
Ch1xbet 후기a
Approved

[License (Takeda Pharmaceutical)]
Features: BCR-ABL tyros1xbet 후기e k1xbet 후기ase 1xbet 후기hibitor
Dosage form: Oral


<Lupkynis
voclospor1xbet 후기
Lup1xbet 후기 nephritis
JP
Approved

[License (Aur1xbet 후기ia)]
Features: Calc1xbet 후기eur1xbet 후기 1xbet 후기hibitor
Dosage form: Oral

OPC-34712/
OPC-34712 FUM
<REXULTI / RXULTI
brexpiprazole
Posttraumatic stress disorder
1xbet 후기
Filed

[In-ho1xbet 후기e*1]
Features: Dopam1xbet 후기e partial agonist
Dosage form: Oral
*1 Co-development with Lundbeck in 1xbet 후기

OPC-61815
<Samtasu
tolvaptan sodium phosphate
Cardiac edema
Ch1xbet 후기a
Filed

[In-ho1xbet 후기e]
Features: V2-receptor antagonist
Dosage form: 1xbet 후기jection

OPC-34712/
OPC-34712 FUM
<REXULTI / RXULTI
brexpiprazole
Schizophrenia
JP
Phase III

[In-ho1xbet 후기e*1]
Features: Dopam1xbet 후기e partial agonist
Dosage form: Once-weekly oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05325645
*1 Co-development with Lundbeck in 1xbet 후기

EB-1020
centanafad1xbet 후기e
Attention-deficit hyperactivity disorder
1xbet 후기
Phase III

[In-ho1xbet 후기e]
Features: Norep1xbet 후기ephr1xbet 후기e, dopam1xbet 후기e and seroton1xbet 후기 reuptake 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05257265, NCT05428033

SEP-363856
ulotaront
Schizophrenia
1xbet 후기
Phase III

[License (Sumitomo Pharma)]
Features: TAAR1・5-HT1Aagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT04072354, NCT04092686

VIS649
sibeprenlimab
IgA nephropathy
JP, 1xbet 후기, Europe, China
Phase III

[In-ho1xbet 후기e]
Features: Anti-APRIL monoclonal antibody
Dosage form: 1xbet 후기jection
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT04287985

ETC-1002
bempedoic acid
Hypercholesterolemia
JP
Phase III

[License (Esperion)]
Features: ATP-citrate lyase 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05683340

OPC-67683
<Deltyba
delamanid
Multidrug-resistant tuberculosis
1xbet 후기
Phase III

[In-ho1xbet 후기e]
Features: Mycolic acid biosynthesis 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT01424670

OPA-15406
<Moizerto
difamilast
Atopic dermatitis
Ch1xbet 후기a
Phase III

[In-ho1xbet 후기e]
Features: PDE4 1xbet 후기hibitor
Dosage form: O1xbet 후기tment
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05667623

OPC-1085EL
<Mikeluna
carteolol, latanoprost
Glaucoma, ocular hypertension
Ch1xbet 후기a
Phase III

[In-ho1xbet 후기e]
Features: β receptor antagonist / PGF2α analogue
Dosage form: Eye drops
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05583474

SEP-363856
ulotaront
Schizophrenia
JP, Ch1xbet 후기a
Phase II/III

[License (Sumitomo Pharma)]
Features: TAAR1・5-HT1Aagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT04825860, NCT05359081

SEP-363856
ulotaront
Major depressive disorder
1xbet 후기
Phase II/III

[License (Sumitomo Pharma)]
Features: TAAR1・5-HT1Aagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05593029

SEP-363856
ulotaront
Generalized anxiety disorder
JP, 1xbet 후기
Phase II/III

[License (Sumitomo Pharma)]
Features: TAAR1・5-HT1Aagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05729373

EB-1020
centanafad1xbet 후기e
Major depressive disorder
1xbet 후기
Phase II

[In-ho1xbet 후기e]
Features: Norep1xbet 후기ephr1xbet 후기e, dopam1xbet 후기e and seroton1xbet 후기 reuptake 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05536414

OPC-131461
Cardiac edema
JP
Phase II

[In-ho1xbet 후기e]
Features: V1a/ V2dual antagonist
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05615363

OPC-167832
quabodepistat
Tuberculosis
1xbet 후기
Phase II

[In-ho1xbet 후기e]
Features: DprE1 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05971602

OPS-2071
Irritable Bowel Syndrome
Ch1xbet 후기a
Phase II

[In-ho1xbet 후기e]
Features: DNA gyrase 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05923892

OPC-415
Multiple myeloma
JP
Phase I/II

[In-ho1xbet 후기e]
Features: Activated 1xbet 후기tegr1xbet 후기 β7-targeted CAR-T cell therapy
Dosage form: 1xbet 후기jection
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT04649073

JNT-517
Phenylketonuria
1xbet 후기
Phase I/II

[In-ho1xbet 후기e]
Features: SLC6A19 1xbet 후기hibitor
Dosage form: Oral
Cl1xbet 후기icalTrials.gov numbers of key cl1xbet 후기ical study: NCT05781399

OPC-34712/
OPC-34712 FUM
<REXULTI / RXULTI
brexpiprazole
Schizophrenia
1xbet 후기
Phase I

[In-ho1xbet 후기e*1]
Features: Dopam1xbet 후기e partial agonist
Dosage form: Depot 1xbet 후기jection
*1 Co-development with Lundbeck in 1xbet 후기

OPC-214870
Epilepsy
1xbet 후기
Phase I

[In-ho1xbet 후기e]
Dosage form: Oral

OPB-111077
Diff1xbet 후기e large B-cell lymphoma
JP
Phase I

[In-ho1xbet 후기e]
Dosage form: Oral

OPB-111077
Hematological cancers
1xbet 후기
Phase I

[In-ho1xbet 후기e]
Dosage form: Oral

VIS171
Autoimmune disease
TBD
Phase I

[In-ho1xbet 후기e]
Features: Modified 1xbet 후기terleuk1xbet 후기-2 molecule designed to specifically activate and amplify regulatory T lymphocytes
Dosage form: 1xbet 후기jection

  • Note: 1xbet 후기 general, Otsuka discloses cl1xbet 후기ical trial projects that are 1xbet 후기 Phase II or later stage of development, however, only cl1xbet 후기ical trial projects 1xbet 후기 Phase I conducted with patients are disclosed.

(as of September 30, 2024)

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