Rehydration

Changes in blood volume following administration 1xbet 로그인 oral rehydration solutions

Morita M, Nose H, Morimoto T
Journal 1xbet 로그인 Clinical and Experimental Medicine 1988; 145: 773-774

Purpose

During dehydration, it is essential to compensate for the decreased blood volume through adequate water replenishment. Few studies have been conducted on the changes in blood volume after fluid intake. The purpose 1xbet 로그인 this study was to determine what changes occur in blood volume after the administration 1xbet 로그인 solutions with different compositions 1xbet 로그인 sodium and glucose by continuously measuring the blood volume in rats.

Methods

An experiment was performed using five male Wistar strain rats, in which the body temperature was maintained at 37℃ under anesthesia. Each rat received one 1xbet 로그인 the test solutions 1xbet 로그인 normal saline (0.9% NaCl), hypertonic saline (1.8% NaCl), a mixture 1xbet 로그인 hypotonic saline (0.45% NaCl) and 2% glucose solution, 5% glucose solution, water or an ion supply drink through a gastrostomy*at a rate 1xbet 로그인 1 mL per 100g 1xbet 로그인 body weight in 10 minutes. The circulating blood volume was continuously measured by the dilution method using51Cr-labeled red 1xbet 로그인 cells.

  • *Gastrostomy is a surgical procedure wherein a tube is inserted through the abdominal wall and into the stomach to provide a means 1xbet 로그인 feeding or hydration.

Results

The rate 1xbet 로그인 blood volume increase was significantly higher in the hypotonic saline + 2% glucose solution, hypertonic saline and ion supply drink groups than in the normal saline group, with the highest rate in the hypotonic saline + 2% glucose solution group. The time at which the blood volume reached equilibrium was longer in the hypertonic saline and normal saline groups. The time to equilibrium was shorter in the hypotonic saline + 2% glucose solution group, followed by the ion supply drink group, with a significant difference between these groups and the normal saline group.

Conclusion

The rate 1xbet 로그인 blood volume increase was higher for the hypotonic saline + 2% glucose solution and ion supply drink compared to normal saline, suggesting the potential influence 1xbet 로그인 glucose on the increase in blood volume.

Change in blood volume after infusion 1xbet 로그인 test solutions
Reference: Modified from Journal 1xbet 로그인 Clinical and Experimental Medicine 1988; 145: 773-774

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